| Gene Information | |
|---|---|
| Gene Name | GRAP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 330 |
| Protein Names | GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000100351 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75791 |
| Gene Card | GRAP2 |
| Uniprot ID | O75791 |
| Pfam | PF00017; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.511929618) |
| Ortholog in Animals | Alpaca_ GRAP2 ( ortholog_one2one ) Dog_ GRAP2 ( ortholog_one2one ) GuineaPig_ GRAP2 ( ortholog_one2one ) Macaque_ GRAP2 ( ortholog_one2one ) Mouse_ Grap2 ( ortholog_one2one ) Pig_ GRAP2 ( ortholog_one2one ) Rat_ Grap2 ( ortholog_one2one ) Rabbit_ GRAP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLA, DAPP1, SH2D5, NCK1, GRAP, GRAPL, GRB2, NCK2, SLA2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.061538(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5GJH (X-ray 1.20A ) |
| DBSNP | rs12759 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21179510}. Cytoplasm {ECO:0000269|PubMed:21179510}. Endosome {ECO:0000269|PubMed:21179510}. |
| Mouse PG classification | NA |
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