| Gene Information | |
|---|---|
| Gene Name | XRCC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 346 |
| Protein Names | DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126215 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43542 |
| Gene Card | XRCC3 |
| Uniprot ID | O43542 |
| Pfam | PF08423 |
| In ASD | no |
| Allosteric Prediction | no (-0.390389559) |
| Ortholog in Animals | Alpaca_ XRCC3 ( ortholog_one2one ) Dog_ XRCC3 ( ortholog_one2one ) GuineaPig_ XRCC3 ( ortholog_one2one ) Macaque_ XRCC3 ( ortholog_one2one ) Mouse_ Xrcc3 ( ortholog_one2one ) Pig_ XRCC3 ( ortholog_one2one ) Rat_ Xrcc3 ( ortholog_one2one ) Rabbit_ XRCC3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RAD51D, RAD51, RAD51C, XRCC2, RAD51B, DMC1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.010102(Chimpanzee);0.029817(Mouse);0.003599(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3212057 rs861539 rs28903080 rs28903081 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion. Note=Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair. |
| Mouse PG classification | NA |
| click here to return to the previous page | |