| Gene Information | |
|---|---|
| Gene Name | FRS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 492 |
| Protein Names | Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000137218 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O43559 |
| Gene Card | FRS3 |
| Uniprot ID | O43559 |
| Pfam | PF02174 |
| In ASD | no |
| Allosteric Prediction | no (-0.504224761) |
| Ortholog in Animals | Alpaca_ FRS3 ( ortholog_one2many ) Dog_ FRS3 ( ortholog_one2one ) GuineaPig_ FRS3 ( ortholog_one2one ) Macaque_ FRS3 ( ortholog_one2one ) Mouse_ Frs3 ( ortholog_one2one ) Pig_ FRS3 ( ortholog_one2one ) Rat_ Frs3 ( ortholog_one2one ) Rabbit_ FRS3 ( ortholog_one2one ) |
| Ohnologs | FRS2 |
| Paralogs | DOK6, DOK4, DOK2, FRS2, DOK1, DOK3, DOK5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KUP (NMR - ) 2KUQ (NMR - ) 2YS5 (NMR - ) 2YT2 (NMR - ) |
| DBSNP | rs3747747 |
| Subcellular location [CC] | Membrane; Lipid-anchor. |
| Mouse PG classification | NA |
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