| Gene Information | |
|---|---|
| Gene Name | CCT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000150753 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | P48643 |
| Gene Card | CCT5 |
| Uniprot ID | P48643 |
| Pfam | PF00118 |
| In ASD | no |
| Allosteric Prediction | yes (0.368254159) |
| Ortholog in Animals | Alpaca_ CCT5 ( ortholog_one2one ) Dog_ CCT5 ( ortholog_one2one ) GuineaPig_ CCT5 ( ortholog_one2one ) Macaque_ CCT5 ( ortholog_one2one ) Mouse_ Cct5 ( ortholog_one2one ) Pig_ CCT5 ( ortholog_one2one ) Rat_ Cct5 ( ortholog_one2one ) Rabbit_ CCT5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TCP1, BBS12, CCT2, CCT6A, CCT4, CCT6B, CCT7, HSPD1, CCT8L2, CCT8, CCT3, PIKFYVE, MKKS |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.382788(Rat);0.194789(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5UYX (X-ray 3.50A ) 5UYZ (X-ray 3.60A ) 6NR8 (EM 7.80A ) 6NR9 (EM 8.50A ) 6NRA (EM 7.70A ) 6NRB (EM 8.70A ) 6NRC (EM 8.30A ) 6NRD (EM 8.20A ) 6QB8 (EM 3.97A ) 7LUM (EM 4.50A ) 7LUP (EM 6.20A ) 7NVL (EM 2.50A ) 7NVM (EM 3.10A ) 7NVN (EM 3.00A ) 7NVO (EM 3.50A ) |
| DBSNP | rs11557652 rs118203986 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20080638}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:20080638}. |
| Mouse PG classification | NA |
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