| Gene Information | |
|---|---|
| Gene Name | PPM1K |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000163644 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N3J5 |
| Gene Card | PPM1K |
| Uniprot ID | Q8N3J5 |
| Pfam | PF00481 |
| In ASD | no |
| Allosteric Prediction | no (-0.52279139) |
| Ortholog in Animals | Alpaca_ PPM1K ( ortholog_one2one ) Dog_ PPM1K ( ortholog_one2one ) GuineaPig_ PPM1K ( ortholog_one2one ) Macaque_ PPM1K ( ortholog_one2one ) Mouse_ Ppm1k ( ortholog_one2one ) Pig_ PPM1K ( ortholog_one2one ) Rat_ Ppm1k ( ortholog_one2one ) Rabbit_ PPM1K ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDP2, TAB1, ILKAP, PPM1B, PPM1L, PPM1N, PP2D1, PDP1, PPM1A, PPM1D, PPM1E, PPM1G, PPM1H, PPM1J, PPM1M, PPM1F |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2IQ1 (X-ray 2.25A ) 4DA1 (X-ray 2.38A ) 6AK7 (X-ray 2.60A ) |
| DBSNP | rs369916009 rs17853762 rs35523553 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:17336929, ECO:0000269|PubMed:17374715}. |
| Mouse PG classification | NA |
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