Gene Information
Gene NameCCSAP
OrganismHomo sapiens (Human)
Gene Length270
Protein NamesCentriole, cilia and spindle-associated protein
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000154429 )
Evolutionary StageEumetazoa
AlphaFoldDBQ6IQ19
Gene CardCCSAP
Uniprot IDQ6IQ19
PfamPF15748
In ASDno
Allosteric Predictionno (-1.329183889)
Ortholog in AnimalsAlpaca_ CCSAP ( ortholog_one2one )
Dog_ CCSAP ( ortholog_one2one )
GuineaPig_ CCSAP ( ortholog_one2one )
Macaque_ CCSAP ( ortholog_one2one )
Mouse_ Ccsap ( ortholog_one2one )
Pig_ CCSAP ( ortholog_one2one )
Rat_ Ccsap ( ortholog_one2one )
Rabbit_ CCSAP ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs6587326 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:22493317, ECO:0000269|PubMed:26562023}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:22493317}. Cell projection, axon {ECO:0000269|PubMed:22493317}. Cell projection, cilium {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:26562023}. Note=Localizes to two to four centrioles throughout the cell cycle. Localizes to mitotic spindle microtubules during prometaphase and throughout the remainder of mitosis. Localizes to cytoskeleton on interphase. Localizes at the ciliary transition zone which connects the basal bodies to ciliary microtubules. Colocalizes with polyglutamylated tubulin. {ECO:0000269|PubMed:22493317, ECO:0000269|PubMed:26562023}.
Mouse PG classificationNA
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