| Gene Information | |
|---|---|
| Gene Name | CCR9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 369 |
| Protein Names | C-C chemokine receptor type 9 (C-C CKR-9) (CC-CKR-9) (CCR-9) (G-protein coupled receptor 28) (GPR-9-6) (CD antigen CDw199) |
| Target Name | c-c chemokine receptor type 9 |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000173585 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P51686 |
| Gene Card | CCR9 |
| Uniprot ID | P51686 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.060411675) |
| Ortholog in Animals | Alpaca_ CCR9 ( ortholog_one2one ) Dog_ CCR9 ( ortholog_one2one ) GuineaPig_ CCR9 ( ortholog_one2one ) Macaque_ CCR9 ( ortholog_one2one ) Mouse_ Ccr9 ( ortholog_one2one ) Pig_ CCR9 ( ortholog_one2one ) Rat_ Ccr9 ( ortholog_one2one ) Rabbit_ CCR9 ( ortholog_one2one ) |
| Ohnologs | CCR6, CCR7, CXCR4, AGTR1 |
| Paralogs | CCR7, ACKR4, CCR10, CXCR6, CCR6, GALR2, XCR1, RGR, ACKR3, CCRL2, CCR8, CCR1, ACKR2, CCR4, CX3CR1, CCR2, CCR5, CCR3, CXCR5, CXCR4, CXCR1, CXCR2, CXCR3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the thymus and low in lymph nodes and spleen. {ECO:0000269|PubMed:10229797, ECO:0000269|PubMed:10640743}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5LWE (X-ray 2.80A ) |
| DBSNP | rs45530037 rs12721497 |
| Subcellular location [CC] | Cell membrane {ECO:0000305|PubMed:27926729}; Multi-pass membrane protein {ECO:0000305|PubMed:27926729}. |
| Mouse PG classification | NA |
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