Gene Information
Gene NameSMIM22
OrganismHomo sapiens (Human)
Gene Length83
Protein NamesSmall integral membrane protein 22 (Cancer-associated small integral membrane open reading frame 1)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000267795 )
Evolutionary StageNA
AlphaFoldDBK7EJ46
Gene CardSMIM22
Uniprot IDK7EJ46
PfamPF15831
In ASDno
Allosteric Predictionno (-1.953665498)
Ortholog in AnimalsAlpaca_ SMIM22 ( ortholog_one2one )
Dog_ SMIM22 ( ortholog_one2one )
GuineaPig_ SMIM22 ( ortholog_one2one )
Macaque_ SMIM22 ( ortholog_one2one )
Mouse_ Smim22 ( ortholog_one2one )
Pig_ SMIM22 ( ortholog_one2one )
Rabbit_ SMIM22 ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissueminor.salivary.gland, small.intestine.Peyers.patch, stomach, testis, transverse.colon
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass membrane protein {ECO:0000305}. Late endosome. Note=Partially colocalizedes with LAMP1 in late endosome. {ECO:0000269|PubMed:29765154}.
Mouse PG classificationNA
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