| Gene Information | |
|---|---|
| Gene Name | CCR10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 362 |
| Protein Names | C-C chemokine receptor type 10 (C-C CKR-10) (CC-CKR-10) (CCR-10) (G-protein coupled receptor 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000184451 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P46092 |
| Gene Card | CCR10 |
| Uniprot ID | P46092 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.867098842) |
| Ortholog in Animals | Alpaca_ CCR10 ( ortholog_one2one ) Dog_ CCR10 ( ortholog_one2one ) GuineaPig_ CCR10 ( ortholog_one2one ) Macaque_ CCR10 ( ortholog_one2one ) Mouse_ Ccr10 ( ortholog_one2one ) Pig_ CCR10 ( ortholog_one2one ) Rat_ Ccr10 ( ortholog_one2one ) Rabbit_ CCR10 ( ortholog_one2one ) |
| Ohnologs | CCR2, ACKR2, CXCR1, CXCR2, CCR4 |
| Paralogs | CCR7, ACKR4, CCR9, CXCR6, CCR6, GALR2, XCR1, RGR, ACKR3, CCRL2, CCR8, CCR1, ACKR2, CCR4, CX3CR1, CCR2, CCR5, CCR3, CXCR5, CXCR4, CXCR1, CXCR2, CXCR3 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells. {ECO:0000269|PubMed:10781587}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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