| Gene Information | |
|---|---|
| Gene Name | HOGA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase) (Protein 569272) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000241935 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q86XE5 |
| Gene Card | HOGA1 |
| Uniprot ID | Q86XE5 |
| Pfam | PF00701 |
| In ASD | no |
| Allosteric Prediction | no (-1.009438609) |
| Ortholog in Animals | Dog_ HOGA1 ( ortholog_one2one ) GuineaPig_ HOGA1 ( ortholog_one2one ) Mouse_ Hoga1 ( ortholog_one2one ) Pig_ HOGA1 ( ortholog_one2one ) Rat_ Hoga1 ( ortholog_one2one ) Rabbit_ HOGA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NPL |
| Tissue | kidney, heart, liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3S5N (X-ray 2.50A ) 3S5O (X-ray 1.97A ) |
| DBSNP | rs267606764 rs138207257 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:Q0P5I5}. |
| Mouse PG classification | HPG |
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