| Gene Information | |
|---|---|
| Gene Name | CCNL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 526 |
| Protein Names | Cyclin-L1 (Cyclin-L) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000163660 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UK58 |
| Gene Card | CCNL1 |
| Uniprot ID | Q9UK58 |
| Pfam | PF02984; PF00134 |
| In ASD | no |
| Allosteric Prediction | no (-0.527938266) |
| Ortholog in Animals | Alpaca_ CCNL1 ( ortholog_one2one ) Dog_ CCNL1 ( ortholog_one2one ) Macaque_ CCNL1 ( ortholog_one2one ) Mouse_ Ccnl1 ( ortholog_one2one ) Pig_ CCNL1 ( ortholog_one2one ) Rat_ Ccnl1 ( ortholog_one2one ) Rabbit_ CCNL1 ( ortholog_one2one ) |
| Ohnologs | CCNL2 |
| Paralogs | CCNT2, CCNK, CCNL2, CCNH, CCNQ, CCNT1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC). {ECO:0000269|PubMed:11980906, ECO:0000269|PubMed:12414649, ECO:0000269|PubMed:15700036, ECO:0000269|PubMed:18216018}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:18216018}. Nucleus, nucleoplasm {ECO:0000269|PubMed:18216018}. Note=Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing. {ECO:0000250}. |
| Mouse PG classification | NA |
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