| Gene Information | |
|---|---|
| Gene Name | LILRA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 499 |
| Protein Names | Leukocyte immunoglobulin-like receptor subfamily A member 4 (CD85 antigen-like family member G) (Immunoglobulin-like transcript 7) (ILT-7) (CD antigen CD85g) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000239961 ) 3 ( ENSG00000274185 ) 3 ( ENSG00000276798 ) 3 ( ENSG00000277092 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P59901 |
| Gene Card | LILRA4 |
| Uniprot ID | P59901 |
| Pfam | PF00047; PF13895 |
| In ASD | no |
| Allosteric Prediction | no (-1.187875146) |
| Ortholog in Animals | Alpaca_ LILRA4 ( ortholog_one2one ) Mouse_ Pira1 ( ortholog_many2many ) Mouse_ Lilra6 ( ortholog_many2many ) Mouse_ Pira12 ( ortholog_many2many ) Mouse_ Pira2 ( ortholog_many2many ) Mouse_ Pira13 ( ortholog_many2many ) Mouse_ Lilra5 ( ortholog_many2many ) Mouse_ Pirb ( ortholog_many2many ) Rat_ Lilrb2 ( ortholog_many2many ) Rat_ Lilra5 ( ortholog_many2many ) Rat_ Lilrc2 ( ortholog_many2many ) Rat_ Lilrb1 ( ortholog_many2many ) Rat_ Lilrb3 ( ortholog_many2many ) Rat_ Lilrb3a ( ortholog_many2many ) Rat_ Lilrb3l ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | LILRB2, LILRB5, LILRA2, LILRB1, LILRA1, LILRA6, LILRA5, LILRB4, LILRB3, NCR1, KIR2DL3, KIR3DL3, KIR3DL2, KIR3DL1, KIR2DS4, KIR2DL4, FCAR, KIR2DL1, GP6, IGSF1, OSCAR, TARM1, VSTM1, LAIR2, A1BG |
| Tissue | lymph.node, spleen |
| Tissue Specificity | Detected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells. {ECO:0000269|PubMed:16735691}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2241384 rs10419832 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16735691, ECO:0000269|PubMed:19564354, ECO:0000269|PubMed:24586760, ECO:0000269|PubMed:26172439}; Single-pass type I membrane protein {ECO:0000305|PubMed:16735691, ECO:0000305|PubMed:19564354, ECO:0000305|PubMed:24586760, ECO:0000305|PubMed:26172439}. |
| Mouse PG classification | NA |
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