| Gene Information | |
|---|---|
| Gene Name | CCNE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | G1/S-specific cyclin-E1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000105173 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P24864 |
| Gene Card | CCNE1 |
| Uniprot ID | P24864 |
| Pfam | PF02984; PF00134 |
| In ASD | no |
| Allosteric Prediction | yes (0.68985153) |
| Ortholog in Animals | Alpaca_ CCNE1 ( ortholog_one2one ) Dog_ CCNE1 ( ortholog_one2one ) GuineaPig_ CCNE1 ( ortholog_one2one ) Macaque_ CCNE1 ( ortholog_one2one ) Mouse_ Ccne1 ( ortholog_one2one ) Rat_ Ccne1 ( ortholog_one2one ) |
| Ohnologs | CCNE2 |
| Paralogs | CCND1, CCNB1, CCNE2, CCNG1, CCNB3, CCNB2, CCNA1, CCNI, CCNP, CCNA2, CCNI2, CCNG2, CCNJL, CCND2, CCNJ, CCNO, CCND3, CCNF |
| Tissue | placenta |
| Tissue Specificity | Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. {ECO:0000269|PubMed:9840943}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1W98 (X-ray 2.15A ) 5L2W (X-ray 2.80A ) 7KJS (X-ray 2.19A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:7739542}. |
| Mouse PG classification | NA |
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