Gene Information
Gene NameABTB1
OrganismHomo sapiens (Human)
Gene Length478
Protein NamesAnkyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000114626 )
Evolutionary StageEukaryota
AlphaFoldDBQ969K4
Gene CardABTB1
Uniprot IDQ969K4
PfamPF12796; PF00651
In ASDno
Allosteric Predictionno (-0.855113873)
Ortholog in AnimalsAlpaca_ ABTB1 ( ortholog_one2one )
Dog_ ABTB1 ( ortholog_one2one )
GuineaPig_ ABTB1 ( ortholog_one2one )
Macaque_ ABTB1 ( ortholog_one2one )
Mouse_ Abtb1 ( ortholog_one2one )
Pig_ ABTB1 ( ortholog_one2one )
Rat_ Abtb1 ( ortholog_one2one )
Rabbit_ ABTB1 ( ortholog_one2one )
OhnologsNA
ParalogsBTBD9, ABTB2, BTBD1, SPOPL, KBTBD4, KLHL11, BTBD6, BTBD2, BTBD3, ABTB3, SPOP
TissueNA
Tissue SpecificityUbiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart. {ECO:0000269|PubMed:10891360}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:11494141}.
Mouse PG classificationNA
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