| Gene Information | |
|---|---|
| Gene Name | CCN6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Cellular communication network factor 6 (CCN family member 6) (WNT1-inducible-signaling pathway protein 3) (WISP-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000112761 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95389 |
| Gene Card | CCN6 |
| Uniprot ID | O95389 |
| Pfam | PF00007; PF00219; PF19035 |
| In ASD | no |
| Allosteric Prediction | no (-1.000142274) |
| Ortholog in Animals | Alpaca_ CCN6 ( ortholog_one2one ) Dog_ CCN6 ( ortholog_one2one ) GuineaPig_ CCN6 ( ortholog_one2one ) Macaque_ CCN6 ( ortholog_one2one ) Mouse_ Ccn6 ( ortholog_one2one ) Pig_ CCN6 ( ortholog_one2one ) Rat_ Ccn6 ( ortholog_one2one ) Rabbit_ CCN6 ( ortholog_one2one ) |
| Ohnologs | CCN4 |
| Paralogs | CCN3, CCN1, CCN2, CCN5, CCN4 |
| Tissue | NA |
| Tissue Specificity | Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found in placenta, ovary, prostate and small intestine (PubMed:9843955, PubMed:10471507). Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes (PubMed:10471507). {ECO:0000269|PubMed:10471507, ECO:0000269|PubMed:9843955}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1230345 rs17073260 rs121908902 rs147337485 rs121908899 rs782813346 rs121908903 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:27252383}. Mitochondrion {ECO:0000269|PubMed:27252383}. Note=Associated with membranes. {ECO:0000269|PubMed:27252383}. |
| Mouse PG classification | NA |
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