| Gene Information | |
|---|---|
| Gene Name | CCN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 432 |
| Protein Names | Cyclin-A2 (Cyclin-A) (Cyclin A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000142871 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P20248 |
| Gene Card | CCNA2 |
| Uniprot ID | P20248 |
| Pfam | PF02984; PF00134; PF16500 |
| In ASD | no |
| Allosteric Prediction | yes (0.264037105) |
| Ortholog in Animals | Alpaca_ CCN1 ( ortholog_one2one ) Dog_ CCN1 ( ortholog_one2one ) GuineaPig_ CCN1 ( ortholog_one2one ) Macaque_ CCN1 ( ortholog_one2one ) Mouse_ Ccn1 ( ortholog_one2one ) Pig_ CCN1 ( ortholog_one2one ) Rat_ Ccn1 ( ortholog_one2one ) Rabbit_ CCN1 ( ortholog_one2one ) |
| Ohnologs | CCN4, CCN3 |
| Paralogs | CCN6, CCN3, CCN2, CCN5, CCN4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.071688(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1E9H (X-ray 2.50A ) 1FIN (X-ray 2.30A ) 1FVV (X-ray 2.80A ) 1GY3 (X-ray 2.70A ) 1H1P (X-ray 2.10A ) 1H1Q (X-ray 2.50A ) 1H1R (X-ray 2.00A ) 1H1S (X-ray 2.00A ) 1H24 (X-ray 2.50A ) 1H25 (X-ray 2.50A ) 1H26 (X-ray 2.24A ) 1H27 (X-ray 2.20A ) 1H28 (X-ray 2.80A ) 1JST (X-ray 2.60A ) 1JSU (X-ray 2.30A ) 1OGU (X-ray 2.60A ) 1OI9 (X-ray 2.10A ) 1OIU (X-ray 2.00A ) 1OIY (X-ray 2.40A ) 1OKV (X-ray 2.40A ) 1OKW (X-ray 2.50A ) 1OL1 (X-ray 2.90A ) 1OL2 (X-ray 2.60A ) 1P5E (X-ray 2.22A ) 1PKD (X-ray 2.30A ) 1QMZ (X-ray 2.20A ) 1URC (X-ray 2.60A ) 1VYW (X-ray 2.30A ) 2BKZ (X-ray 2.60A ) 2BPM (X-ray 2.40A ) 2C4G (X-ray 2.70A ) 2C5N (X-ray 2.10A ) 2C5O (X-ray 2.10A ) 2C5V (X-ray 2.90A ) 2C5X (X-ray 2.90A ) 2C6T (X-ray 2.61A ) 2CCH (X-ray 1.70A ) 2CCI (X-ray 2.70A ) 2CJM (X-ray 2.30A ) 2I40 (X-ray 2.80A ) 2IW6 (X-ray 2.30A ) 2IW8 (X-ray 2.30A ) 2IW9 (X-ray 2.00A ) 2UUE (X-ray 2.06A ) 2UZB (X-ray 2.70A ) 2UZD (X-ray 2.72A ) 2UZE (X-ray 2.40A ) 2UZL (X-ray 2.40A ) 2V22 (X-ray 2.60A ) 2WEV (X-ray 2.30A ) 2WFY (X-ray 2.53A ) 2WHB (X-ray 2.90A ) 2WIH (X-ray 2.50A ) 2WIP (X-ray 2.80A ) 2WMA (X-ray 2.80A ) 2WMB (X-ray 2.60A ) 2WPA (X-ray 2.51A ) 2WXV (X-ray 2.60A ) 2X1N (X-ray 2.75A ) 3EID (X-ray 3.15A ) 3EJ1 (X-ray 3.22A ) 3EOC (X-ray 3.20A ) 3F5X (X-ray 2.40A ) 4BCK (X-ray 2.05A ) 4BCM (X-ray 2.45A ) 4BCN (X-ray 2.10A ) 4BCP (X-ray 2.26A ) 4CFM (X-ray 2.85A ) 4CFN (X-ray 2.20A ) 4CFU (X-ray 2.20A ) 4CFV (X-ray 2.00A ) 4CFW (X-ray 2.45A ) 4CFX (X-ray 3.50A ) 4EOI (X-ray 2.00A ) 4EOJ (X-ray 1.65A ) 4EOK (X-ray 2.57A ) 4EOL (X-ray 2.40A ) 4EOM (X-ray 2.10A ) 4EON (X-ray 2.40A ) 4EOO (X-ray 2.10A ) 4EOP (X-ray 1.99A ) 4EOQ (X-ray 2.15A ) 4EOR (X-ray 2.20A ) 4EOS (X-ray 2.57A ) 4FX3 (X-ray 2.75A ) 5CYI (X-ray 2.00A ) 5IF1 (X-ray 2.61A ) 5LMK (X-ray 2.40A ) 5NEV (X-ray 2.97A ) 6ATH (X-ray 1.82A ) 6GVA (X-ray 2.15A ) 6P3W (X-ray 2.54A ) 6Q6G (EM 3.20A ) 6Q6H (EM 3.20A ) 6RIJ (X-ray 2.20A ) 6SG4 (X-ray 2.43A ) 7ACK (X-ray 1.80A ) 7B5L (EM 3.80A ) 7B5R (EM 3.80A ) 7B7S (X-ray 2.54A ) 7LUO (X-ray 3.17A ) 7QHL (X-ray 1.70A ) |
| DBSNP | rs769242 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:1312467, ECO:0000269|PubMed:17698606}. Cytoplasm {ECO:0000269|PubMed:1312467, ECO:0000269|PubMed:17698606}. Note=Exclusively nuclear during interphase (PubMed:1312467). Detected in the nucleus and the cytoplasm at prophase (PubMed:1312467). Cytoplasmic when associated with SCAPER (PubMed:17698606). {ECO:0000269|PubMed:1312467, ECO:0000269|PubMed:17698606}. |
| Mouse PG classification | NA |
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