| Gene Information | |
|---|---|
| Gene Name | CCL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 92 |
| Protein Names | C-C motif chemokine 4 (G-26 T-lymphocyte-secreted protein) (HC21) (Lymphocyte activation gene 1 protein) (LAG-1) (MIP-1-beta(1-69)) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (PAT 744) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4) (T-cell activation protein 2) (ACT-2) [Cleaved into: MIP-1-beta(3-69)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000275302 ) 3 ( ENSG00000275824 ) 3 ( ENSG00000277943 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P13236 |
| Gene Card | CCL4 |
| Uniprot ID | P13236 |
| Pfam | PF00048 |
| In ASD | no |
| Allosteric Prediction | yes (0.129304852) |
| Ortholog in Animals | Mouse_ Ccl4 ( ortholog_one2many ) Rat_ Ccl4 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | CCL25, CCL21, XCL1, CCL20, CCL19, XCL2, CCL22, CCL17, CCL4L2, CCL15, CCL18, CCL3L3, CCL3, CCL23, CCL14, CCL16, CCL24, CCL26, CCL2, CCL13, CCL8, CCL7, CCL11, CCL1, CX3CL1 |
| Tissue | spleen, whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HUM (NMR - ) 1HUN (NMR - ) 1JE4 (NMR - ) 2FFK (NMR - ) 2FIN (NMR - ) 2X6L (X-ray 2.60A ) 3TN2 (X-ray 1.60A ) 4RAL (X-ray 3.15A ) |
| DBSNP | rs1049752 rs1130750 rs1719152 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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