| Gene Information | |
|---|---|
| Gene Name | CCL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 92 |
| Protein Names | C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))] |
| Target Name | c-c motif chemokine 3 |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000274221 ) 424 ( ENSG00000277632 ) 3 ( ENSG00000278567 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P10147 |
| Gene Card | CCL3 |
| Uniprot ID | P10147 |
| Pfam | PF00048 |
| In ASD | no |
| Allosteric Prediction | no (-0.065777453) |
| Ortholog in Animals | Alpaca_ CCL3 ( ortholog_one2many ) Dog_ CCL3 ( ortholog_one2many ) Mouse_ Ccl3 ( ortholog_one2many ) Rat_ Ccl3 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | CCL25, CCL21, XCL1, CCL20, CCL19, XCL2, CCL22, CCL17, CCL3L3, CCL18, CCL15, CCL23, CCL14, CCL4, CCL4L2, CCL16, CCL24, CCL26, CCL2, CCL13, CCL8, CCL7, CCL11, CCL1, CX3CL1 |
| Tissue | spleen, whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1B50 (NMR - ) 1B53 (NMR - ) 2X69 (X-ray 2.65A ) 2X6G (X-ray 2.18A ) 3FPU (X-ray 1.76A ) 3H44 (X-ray 3.00A ) 3KBX (X-ray 2.65A ) 4RA8 (X-ray 2.60A ) 4ZKB (X-ray 2.90A ) 5COR (X-ray 2.55A ) 5D65 (X-ray 3.10A ) 7F1Q (EM 2.90A ) 7F1T (X-ray 2.60A ) |
| DBSNP | rs34171309 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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