| Gene Information | |
|---|---|
| Gene Name | CCL15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 113 |
| Protein Names | C-C motif chemokine 15 (Chemokine CC-2) (HCC-2) (Leukotactin-1) (LKN-1) (MIP-1 delta) (Macrophage inflammatory protein 5) (MIP-5) (Mrp-2b) (NCC-3) (Small-inducible cytokine A15) [Cleaved into: CCL15(22-92); CCL15(25-92); CCL15(29-92)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000275528 ) 424 ( ENSG00000275718 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q16663 |
| Gene Card | CCL15 |
| Uniprot ID | Q16663 |
| Pfam | PF00048 |
| In ASD | no |
| Allosteric Prediction | no (-0.474958959) |
| Ortholog in Animals | Alpaca_ CCL15 ( ortholog_one2one ) Dog_ CCL23 ( ortholog_one2many ) Macaque_ CCL15 ( ortholog_one2one ) Mouse_ Ccl6 ( ortholog_many2many ) Mouse_ Ccl9 ( ortholog_many2many ) Rat_ Ccl9 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | CCL25, CCL21, XCL1, CCL20, CCL19, XCL2, CCL22, CCL17, CCL23, CCL14, CCL18, CCL3L3, CCL3, CCL4, CCL4L2, CCL16, CCL24, CCL26, CCL2, CCL13, CCL8, CCL7, CCL11, CCL1, CX3CL1 |
| Tissue | NA |
| Tissue Specificity | Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients. {ECO:0000269|PubMed:15905581, ECO:0000269|PubMed:9558365}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HCC (NMR - ) 7VL9 (EM 2.60A ) 7VLA (EM 2.70A ) |
| DBSNP | rs854625 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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