| Gene Information | |
|---|---|
| Gene Name | AGO3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 860 |
| Protein Names | Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000126070 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H9G7 |
| Gene Card | AGO3 |
| Uniprot ID | Q9H9G7 |
| Pfam | PF08699; PF16488; PF16487; PF16486; PF02170; PF02171 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000202778) |
| Ortholog in Animals | Alpaca_ AGO3 ( ortholog_one2one ) Dog_ AGO3 ( ortholog_one2one ) GuineaPig_ AGO3 ( ortholog_one2one ) Macaque_ AGO3 ( ortholog_one2one ) Mouse_ Ago3 ( ortholog_one2one ) Pig_ AGO3 ( ortholog_one2one ) Rat_ Ago3 ( ortholog_one2one ) Rabbit_ AGO3 ( ortholog_one2one ) |
| Ohnologs | AGO2 |
| Paralogs | AGO4, AGO1, AGO2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.00625(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 5VM9 (X-ray 3.28A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, P-body {ECO:0000255|HAMAP-Rule:MF_03032, ECO:0000269|PubMed:16081698}. |
| Mouse PG classification | NA |
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