| Gene Information | |
|---|---|
| Gene Name | PDS5A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1337 |
| Protein Names | Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000121892 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q29RF7 |
| Gene Card | PDS5A |
| Uniprot ID | Q29RF7 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.483077504) |
| Ortholog in Animals | Alpaca_ PDS5A ( ortholog_one2one ) Dog_ PDS5A ( ortholog_one2one ) GuineaPig_ PDS5A ( ortholog_one2one ) Macaque_ PDS5A ( ortholog_one2one ) Mouse_ Pds5a ( ortholog_one2one ) Pig_ PDS5A ( ortholog_one2one ) Rat_ Pds5a ( ortholog_one2one ) Rabbit_ PDS5A ( ortholog_one2one ) |
| Ohnologs | PDS5B |
| Paralogs | PDS5B |
| Tissue | NA |
| Tissue Specificity | Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. {ECO:0000269|PubMed:15019998}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001790(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11076961, ECO:0000269|PubMed:15019998}. Note=Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase. {ECO:0000269|PubMed:11076961, ECO:0000269|PubMed:15019998}. |
| Mouse PG classification | NA |
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