| Gene Information | |
|---|---|
| Gene Name | LTBR |
| Organism | Homo sapiens (Human) |
| Gene Length | 435 |
| Protein Names | Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III) |
| Target Name | lymphotoxin beta receptor |
| Target Type | Clinical trial target |
| Gene Age | 987 ( ENSG00000111321 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P36941 |
| Gene Card | LTBR |
| Uniprot ID | P36941 |
| Pfam | PF00020 |
| In ASD | no |
| Allosteric Prediction | no (-0.278711876) |
| Ortholog in Animals | Alpaca_ LTBR ( ortholog_one2one ) Dog_ LTBR ( ortholog_one2one ) GuineaPig_ LTBR ( ortholog_one2one ) Macaque_ LTBR ( ortholog_one2one ) Mouse_ Ltbr ( ortholog_one2one ) Pig_ LTBR ( ortholog_one2one ) Rat_ Ltbr ( ortholog_one2one ) Rabbit_ LTBR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TNFRSF25, TNFRSF6B, CD40, TNFRSF21, TNFRSF1A, TNFRSF10C, TNFRSF11B, TNFRSF10B, TNFRSF11A, CD27, NGFR, FAS, TNFRSF10A, TNFRSF9, TNFRSF18, TNFRSF8, RELT, TNFRSF10D, TNFRSF4, TNFRSF14, TNFRSF1B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RF3 (X-ray 3.50A ) 4MXW (X-ray 3.60A ) |
| DBSNP | rs35681405 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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