| Gene Information | |
|---|---|
| Gene Name | PDRO |
| Organism | Homo sapiens (Human) |
| Gene Length | 161 |
| Protein Names | Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6IAA8 |
| Gene Card | LAMTOR1 |
| Uniprot ID | Q6IAA8 |
| Pfam | PF15454 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.047562(Rat);0.150548(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5X6U (X-ray 2.40A ) 5X6V (X-ray 2.02A ) 5Y39 (X-ray 2.65A ) 5Y3A (X-ray 2.90A ) 6B9X (X-ray 1.42A ) 6EHP (X-ray 2.30A ) 6EHR (X-ray 2.90A ) 6NZD (EM 3.60A ) 6U62 (EM 3.18A ) 6ULG (EM 3.31A ) 6WJ2 (EM 3.20A ) 6WJ3 (EM 3.90A ) 7T3A (EM 4.00A ) 7T3B (EM 3.90A ) 7T3C (EM 4.00A ) |
| DBSNP | rs1053443 |
| Subcellular location [CC] | Late endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane {ECO:0000269|PubMed:20544018}; Lipid-anchor; Cytoplasmic side. Cell membrane. |
| Mouse PG classification | NA |
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