| Gene Information | |
|---|---|
| Gene Name | PPLA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 148 |
| Protein Names | Phospholipase A2 (EC 3.1.1.4) (Group IB phospholipase A2) (Phosphatidylcholine 2-acylhydrolase 1B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P04054 |
| Gene Card | PLA2G1B |
| Uniprot ID | P04054 |
| Pfam | PF00068 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Selectively expressed in pancreas, lung, liver and kidney. Also detected at lower levels in ovary and testis. {ECO:0000269|PubMed:10681567}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ELO (X-ray 1.55A ) 6Q42 (X-ray 1.90A ) |
| DBSNP | rs5632 rs5636 rs5635 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:19297324}. Note=Secreted from pancreatic acinar cells in its inactive form. |
| Mouse PG classification | NA |
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