| Gene Information | |
|---|---|
| Gene Name | LRRC25 |
| Organism | Homo sapiens (Human) |
| Gene Length | 305 |
| Protein Names | Leucine-rich repeat-containing protein 25 (Monocyte and plasmacytoid-activated protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000175489 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8N386 |
| Gene Card | LRRC25 |
| Uniprot ID | Q8N386 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.691912436) |
| Ortholog in Animals | Alpaca_ LRRC25 ( ortholog_one2one ) Dog_ LRRC25 ( ortholog_one2one ) Macaque_ LRRC25 ( ortholog_one2one ) Mouse_ Lrrc25 ( ortholog_one2one ) Pig_ LRRC25 ( ortholog_one2one ) Rat_ Lrrc25 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | whole.blood |
| Tissue Specificity | Expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus. {ECO:0000269|PubMed:12384430}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34439430 rs6512265 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:29044191}. |
| Mouse PG classification | NA |
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