| Gene Information | |
|---|---|
| Gene Name | PACS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 889 |
| Protein Names | Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000179364 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86VP3 |
| Gene Card | PACS2 |
| Uniprot ID | Q86VP3 |
| Pfam | PF10254 |
| In ASD | no |
| Allosteric Prediction | no (-0.174177446) |
| Ortholog in Animals | Alpaca_ PACS2 ( ortholog_one2one ) Dog_ PACS2 ( ortholog_one2one ) GuineaPig_ PACS2 ( ortholog_one2one ) Macaque_ PACS2 ( ortholog_one2one ) Mouse_ Pacs2 ( ortholog_one2one ) Pig_ PACS2 ( ortholog_one2one ) Rat_ Pacs2 ( ortholog_one2one ) Rabbit_ PACS2 ( ortholog_one2one ) |
| Ohnologs | PACS1 |
| Paralogs | PACS1 |
| Tissue | NA |
| Tissue Specificity | Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. {ECO:0000269|PubMed:15692567}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8010888 rs1555408401 rs4076933 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:15692567}. Mitochondrion {ECO:0000269|PubMed:15692567}. |
| Mouse PG classification | NA |
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