| Gene Information | |
|---|---|
| Gene Name | CLDND1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 253 |
| Protein Names | Claudin domain-containing protein 1 (Membrane protein GENX-3745) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000080822 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NY35 |
| Gene Card | CLDND1 |
| Uniprot ID | Q9NY35 |
| Pfam | PF13903 |
| In ASD | no |
| Allosteric Prediction | no (-1.049378786) |
| Ortholog in Animals | Alpaca_ CLDND1 ( ortholog_one2one ) Dog_ CLDND1 ( ortholog_one2one ) GuineaPig_ CLDND1 ( ortholog_one2one ) Macaque_ CLDND1 ( ortholog_one2one ) Mouse_ Cldnd1 ( ortholog_one2one ) Pig_ CLDND1 ( ortholog_one2one ) Rat_ Cldnd1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely distributed in the adult CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. Weak expression was detected in the adult heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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