| Gene Information | |
|---|---|
| Gene Name | MDGA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 956 |
| Protein Names | MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000139915 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q7Z553 |
| Gene Card | MDGA2 |
| Uniprot ID | Q7Z553 |
| Pfam | PF07679; PF00629 |
| In ASD | no |
| Allosteric Prediction | no (-1.487498161) |
| Ortholog in Animals | Alpaca_ MDGA2 ( ortholog_one2one ) Dog_ MDGA2 ( ortholog_one2one ) GuineaPig_ MDGA2 ( ortholog_one2one ) Macaque_ MDGA2 ( ortholog_one2one ) Mouse_ Mdga2 ( ortholog_one2one ) Pig_ MDGA2 ( ortholog_one2one ) Rat_ Mdga2 ( ortholog_one2one ) Rabbit_ MDGA2 ( ortholog_one2one ) |
| Ohnologs | MDGA1 |
| Paralogs | MALRD1, MAMDC2, MAMDC4, MDGA1 |
| Tissue | NA |
| Tissue Specificity | Detected in Leydig cells, syncytiotrophoblast, duodenal villi epithelial cells and neutrophils from kidney and cutaneous squamous cell carcinoma (at protein level). {ECO:0000269|PubMed:19997561}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12590500 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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