| Gene Information | |
|---|---|
| Gene Name | CERS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 350 |
| Protein Names | Ceramide synthase 1 (CerS1) (LAG1 longevity assurance homolog 1) (Longevity assurance gene 1 protein homolog 1) (Protein UOG-1) (Sphingoid base N-stearoyltransferase CERS1) (EC 2.3.1.299) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000223802 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P27544 |
| Gene Card | CERS1 |
| Uniprot ID | P27544 |
| Pfam | PF03798 |
| In ASD | no |
| Allosteric Prediction | no (-0.477601279) |
| Ortholog in Animals | Alpaca_ CERS1 ( ortholog_one2one ) Dog_ CERS1 ( ortholog_one2one ) GuineaPig_ CERS1 ( ortholog_one2one ) Macaque_ CERS1 ( ortholog_one2one ) Pig_ CERS1 ( ortholog_one2one ) Rat_ Cers1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CERS5, CERS3, CERS4, CERS2, CERS6 |
| Tissue | brain |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs200024180 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:24782409}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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