| Gene Information | |
|---|---|
| Gene Name | PLK5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 336 |
| Protein Names | Inactive serine/threonine-protein kinase PLK5 (Polo-like kinase 5) (PLK-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000185988 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q496M5 |
| Gene Card | PLK5 |
| Uniprot ID | Q496M5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.821724167) |
| Ortholog in Animals | Alpaca_ PLK5 ( ortholog_one2one ) Dog_ PLK5 ( ortholog_one2one ) Mouse_ Plk5 ( ortholog_one2one ) Rat_ Plk5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PLK3, PLK1, PLK2, PLK4 |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level). {ECO:0000269|PubMed:21245385}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:21245385}. |
| Mouse PG classification | NA |
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