| Gene Information | |
|---|---|
| Gene Name | CC2D2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1620 |
| Protein Names | Coiled-coil and C2 domain-containing protein 2A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000048342 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P2K1 |
| Gene Card | CC2D2A |
| Uniprot ID | Q9P2K1 |
| Pfam | PF00168; PF15625; PF17661 |
| In ASD | no |
| Allosteric Prediction | no (-1.120537141) |
| Ortholog in Animals | Alpaca_ CC2D2A ( ortholog_one2one ) Dog_ CC2D2A ( ortholog_one2one ) GuineaPig_ CC2D2A ( ortholog_one2one ) Macaque_ CC2D2A ( ortholog_one2one ) Mouse_ Cc2d2a ( ortholog_one2one ) Pig_ CC2D2A ( ortholog_one2one ) Rat_ Cc2d2a ( ortholog_one2one ) Rabbit_ CC2D2A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CEP76, CC2D2B |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in prostate, pancreas, kidney, lung, liver, retina, kidney, fetal brain and fetal kidney. Lower expression in spleen, small intestine, colon, skeletal muscle, ovary, thymus and heart. {ECO:0000269|PubMed:18387594, ECO:0000269|PubMed:18950740}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs186264635 rs16892095 rs144439937 rs754221308 rs16892134 rs190698163 rs537906621 rs199768782 rs751256652 rs200707391 rs863225173 rs863225169 rs386833752 rs267606709 rs118204051 rs1473532901 rs863225170 rs386833755 rs779823379 rs754586025 rs763486732 rs863225168 rs387907058 rs780673487 rs1478902342 rs118204052 rs763425007 rs201502401 |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}. |
| Mouse PG classification | NA |
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