| Gene Information | |
|---|---|
| Gene Name | CBX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 183 |
| Protein Names | Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000122565 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13185 |
| Gene Card | CBX3 |
| Uniprot ID | Q13185 |
| Pfam | PF00385; PF01393 |
| In ASD | no |
| Allosteric Prediction | no (-0.510905453) |
| Ortholog in Animals | Alpaca_ CBX3 ( ortholog_one2one ) Dog_ CBX3 ( ortholog_one2one ) GuineaPig_ CBX3 ( ortholog_one2one ) Macaque_ CBX3 ( ortholog_one2one ) Mouse_ Cbx3 ( ortholog_one2one ) Rat_ Cbx3 ( ortholog_one2one ) |
| Ohnologs | CBX5, CBX1 |
| Paralogs | CBX6, NPTXR, CBX1, CBX4, CBX7, CBX2, CBX5, CBX8 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);0.029715(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L11 (NMR - ) 3DM1 (X-ray 2.40A ) 3KUP (X-ray 1.77A ) 3TZD (X-ray 1.81A ) 5T1I (X-ray 1.60A ) 6HW2 (X-ray 1.94A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). {ECO:0000305}. |
| Mouse PG classification | NA |
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