| Gene Information | |
|---|---|
| Gene Name | GRIK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 919 |
| Protein Names | Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7) |
| Target Name | glutamate receptor ionotropic kainate 3 |
| Target Type | Literature-reported target |
| Gene Age | 950 ( ENSG00000163873 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13003 |
| Gene Card | GRIK3 |
| Uniprot ID | Q13003 |
| Pfam | PF01094; PF00060; PF10613 |
| In ASD | no |
| Allosteric Prediction | yes (0.686674359) |
| Ortholog in Animals | Alpaca_ GRIK3 ( ortholog_one2one ) Dog_ GRIK3 ( ortholog_one2one ) GuineaPig_ GRIK3 ( ortholog_one2one ) Macaque_ GRIK3 ( ortholog_one2one ) Mouse_ Grik3 ( ortholog_one2one ) Pig_ GRIK3 ( ortholog_one2one ) Rat_ Grik3 ( ortholog_one2one ) Rabbit_ GRIK3 ( ortholog_one2one ) |
| Ohnologs | GRIK5, GRIK4, GRIK2, GRIK1 |
| Paralogs | GRIN3A, GRIN2A, GRIK5, GRIN2C, GRID1, GRID2, GRIN2D, GRIN1, GRIK4, GRIA3, GRIK1, GRIA2, GRIA1, GRIN3B, GRIK2, GRIA4, GRIN2B |
| Tissue | brain |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs755366301 rs6691840 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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