| Gene Information | |
|---|---|
| Gene Name | NFE2L3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 694 |
| Protein Names | Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000050344 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y4A8 |
| Gene Card | NFE2L3 |
| Uniprot ID | Q9Y4A8 |
| Pfam | PF03131 |
| In ASD | no |
| Allosteric Prediction | no (-1.37702633) |
| Ortholog in Animals | Alpaca_ NFE2L3 ( ortholog_one2one ) Dog_ NFE2L3 ( ortholog_one2one ) GuineaPig_ NFE2L3 ( ortholog_one2one ) Macaque_ NFE2L3 ( ortholog_one2one ) Mouse_ Nfe2l3 ( ortholog_one2one ) Pig_ NFE2L3 ( ortholog_one2one ) Rat_ Nfe2l3 ( ortholog_one2one ) Rabbit_ NFE2L3 ( ortholog_one2one ) |
| Ohnologs | NFE2L1 |
| Paralogs | NFE2L1, NFE2, NFE2L2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10037736}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2072129 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}. |
| Mouse PG classification | NA |
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