| Gene Information | |
|---|---|
| Gene Name | EPB41L3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1087 |
| Protein Names | Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000082397 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9Y2J2 |
| Gene Card | EPB41L3 |
| Uniprot ID | Q9Y2J2 |
| Pfam | PF05902; PF08736; PF09380; PF00373; PF09379; PF04382 |
| In ASD | no |
| Allosteric Prediction | yes (0.044042583) |
| Ortholog in Animals | Alpaca_ EPB41L3 ( ortholog_one2one ) Dog_ EPB41L3 ( ortholog_one2one ) GuineaPig_ EPB41L3 ( ortholog_one2one ) Macaque_ EPB41L3 ( ortholog_one2one ) Mouse_ Epb41l3 ( ortholog_one2one ) Pig_ EPB41L3 ( ortholog_one2one ) Rat_ Epb41l3 ( ortholog_one2one ) Rabbit_ EPB41L3 ( ortholog_one2one ) |
| Ohnologs | EPB41L2, EPB41 |
| Paralogs | EPB41L2, FRMD3, EPB41, EPB41L5, FRMD6, FRMD5, EPB41L4B, EPB41L4A, MYLIP, EPB41L1 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung. {ECO:0000269|PubMed:9892180}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 2HE7 (X-ray 2.00A ) 3BIN (X-ray 2.30A ) 5RYM (X-ray 1.64A ) 5RYN (X-ray 1.88A ) 5RYO (X-ray 1.58A ) 5RYP (X-ray 1.63A ) 5RYQ (X-ray 1.64A ) 5RYR (X-ray 1.87A ) 5RYS (X-ray 1.75A ) 5RYT (X-ray 1.72A ) 5RYU (X-ray 1.63A ) 5RYV (X-ray 1.69A ) 5RYW (X-ray 1.66A ) 5RYX (X-ray 1.63A ) 5RYY (X-ray 1.69A ) 5RYZ (X-ray 1.61A ) 5RZ0 (X-ray 1.74A ) 5RZ1 (X-ray 1.62A ) 5RZ2 (X-ray 1.77A ) 5RZ3 (X-ray 1.74A ) 5RZ4 (X-ray 1.61A ) 5RZ5 (X-ray 1.63A ) 5RZ6 (X-ray 1.64A ) 5RZ7 (X-ray 1.76A ) 5RZ8 (X-ray 1.66A ) 5RZ9 (X-ray 1.79A ) 5RZA (X-ray 1.89A ) 5RZB (X-ray 1.59A ) 5RZC (X-ray 1.75A ) 5RZD (X-ray 1.81A ) 5RZE (X-ray 1.69A ) 5RZF (X-ray 1.76A ) 5RZG (X-ray 1.70A ) 5RZH (X-ray 1.88A ) 5RZI (X-ray 2.09A ) 5RZJ (X-ray 1.68A ) 5RZK (X-ray 1.84A ) 5RZL (X-ray 1.71A ) 5RZM (X-ray 1.71A ) 5RZN (X-ray 1.83A ) 5RZO (X-ray 1.97A ) 5RZP (X-ray 1.70A ) 5RZQ (X-ray 1.88A ) 5RZR (X-ray 1.78A ) 5RZS (X-ray 1.69A ) 5RZT (X-ray 1.79A ) 5RZU (X-ray 1.66A ) 5RZV (X-ray 1.75A ) 5RZW (X-ray 1.62A ) 5RZX (X-ray 1.74A ) 5RZY (X-ray 1.75A ) 5RZZ (X-ray 1.76A ) 5S00 (X-ray 1.77A ) 6IBE (X-ray 1.45A ) |
| DBSNP | rs9966357 rs8082898 rs8096452 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction {ECO:0000269|PubMed:9892180}. Cell membrane {ECO:0000269|PubMed:9892180}; Peripheral membrane protein {ECO:0000269|PubMed:9892180}; Cytoplasmic side {ECO:0000269|PubMed:9892180}. Cytoplasm {ECO:0000269|PubMed:9892180}. Note=Detected in the cytoplasm of actively dividing cells. |
| Mouse PG classification | NA |
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