| Gene Information | |
|---|---|
| Gene Name | CATSPER1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 780 |
| Protein Names | Cation channel sperm-associated protein 1 (CatSper1) (hCatSper) |
| Target Name | cation channel sperm-associated protein 1 |
| Target Type | Literature-reported target |
| Gene Age | 424 ( ENSG00000175294 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NEC5 |
| Gene Card | CATSPER1 |
| Uniprot ID | Q8NEC5 |
| Pfam | PF00520 |
| In ASD | no |
| Allosteric Prediction | yes (0.166732256) |
| Ortholog in Animals | Alpaca_ CATSPER1 ( ortholog_one2one ) Dog_ CATSPER1 ( ortholog_one2one ) Macaque_ CATSPER1 ( ortholog_one2one ) Mouse_ Catsper1 ( ortholog_one2one ) Pig_ CATSPER1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCN11A, CACNA1C, CACNA1E, CACNA1I, SCN9A, CACNA1B, SCN7A, SCN3A, SCN5A, SCN2A, SCN1A, CACNA1A, CACNA1F, CACNA1H, CATSPER2, CACNA1G, SCN8A, NALCN, CACNA1D, CATSPER4, SCN10A, CACNA1S, CATSPER3, TPCN1, TPCN2, SCN4A |
| Tissue | testis |
| Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:11595941, ECO:0000269|PubMed:16625279, ECO:0000269|PubMed:17347248}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1203998 rs3814747 rs34958219 |
| Subcellular location [CC] | Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:16625279}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q91ZR5}. Note=Specifically located in the principal piece of the sperm tail. {ECO:0000269|PubMed:16625279}. |
| Mouse PG classification | HPG |
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