| Gene Information | |
|---|---|
| Gene Name | PHF21A |
| Organism | Homo sapiens (Human) |
| Gene Length | 680 |
| Protein Names | PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135365 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96BD5 |
| Gene Card | PHF21A |
| Uniprot ID | Q96BD5 |
| Pfam | PF00628 |
| In ASD | no |
| Allosteric Prediction | no (-0.268220573) |
| Ortholog in Animals | Alpaca_ PHF21A ( ortholog_one2one ) Dog_ PHF21A ( ortholog_one2one ) GuineaPig_ PHF21A ( ortholog_one2one ) Macaque_ PHF21A ( ortholog_one2one ) Mouse_ Phf21a ( ortholog_one2one ) Pig_ PHF21A ( ortholog_one2one ) Rat_ Phf21a ( ortholog_one2one ) Rabbit_ PHF21A ( ortholog_one2one ) |
| Ohnologs | PHF21B |
| Paralogs | PHF12, ZMYND11, AIRE, PHF21B, ZMYND8 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain (PubMed:31649809). Expressed at lower level in other tissues, including heart, kidney, liver, lung and skeletal muscle (PubMed:31649809). Abundantly expressed in fetal brain (PubMed:31649809). {ECO:0000269|PubMed:12032298, ECO:0000269|PubMed:31649809}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.076923(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2PUY (X-ray 1.43A ) 2YQL (NMR - ) |
| DBSNP | rs3736508 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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