| Gene Information | |
|---|---|
| Gene Name | IER2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 223 |
| Protein Names | Immediate early response gene 2 protein (Protein ETR101) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000160888 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BTL4 |
| Gene Card | IER2 |
| Uniprot ID | Q9BTL4 |
| Pfam | PF05760 |
| In ASD | no |
| Allosteric Prediction | no (-1.38302777) |
| Ortholog in Animals | Alpaca_ IER2 ( ortholog_one2one ) Dog_ IER2 ( ortholog_one2one ) Mouse_ Ier2 ( ortholog_one2one ) Pig_ IER2 ( ortholog_one2one ) Rat_ Ier2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IER5L, IER5 |
| Tissue | NA |
| Tissue Specificity | Expressed in activated T-cells (at protein level) (PubMed:22120713). Expression increases in metastatic tumor cells (at protein level) (PubMed:22120713). {ECO:0000269|PubMed:22120713}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1042164 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22120713}. Nucleus {ECO:0000269|PubMed:22120713}. Note=Cytoplasmic during quiescence, translocates to the nucleus upon stimulation. {ECO:0000269|PubMed:22120713}. |
| Mouse PG classification | NA |
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