| Gene Information | |
|---|---|
| Gene Name | CASTOR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 329 |
| Protein Names | Cytosolic arginine sensor for mTORC1 subunit 1 (Cellular arginine sensor for mTORC1 protein 1) (GATS-like protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000239282 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WTX7 |
| Gene Card | CASTOR1 |
| Uniprot ID | Q8WTX7 |
| Pfam | PF13840; PF18700 |
| In ASD | yes |
| Allosteric Prediction | no (-0.91761103) |
| Ortholog in Animals | Alpaca_ CASTOR1 ( ortholog_one2one ) Dog_ CASTOR1 ( ortholog_one2one ) GuineaPig_ CASTOR1 ( ortholog_one2one ) Mouse_ Castor1 ( ortholog_one2one ) Pig_ CASTOR1 ( ortholog_one2one ) Rat_ Castor1 ( ortholog_one2one ) Rabbit_ CASTOR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CASTOR2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000303|PubMed:26972053}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.050650(Mouse);0.001000(Rat);0.040000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5GS9 (X-ray 2.50A ) 5GT7 (X-ray 2.05A ) 5GT8 (X-ray 2.80A ) 5GV2 (X-ray 2.06A ) 5I2C (X-ray 1.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:26972053}. |
| Mouse PG classification | NA |
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