| Gene Information | |
|---|---|
| Gene Name | CD300LF |
| Organism | Homo sapiens (Human) |
| Gene Length | 290 |
| Protein Names | CMRF35-like molecule 1 (CLM-1) (CD300 antigen-like family member F) (Immune receptor expressed on myeloid cells 1) (IREM-1) (Immunoglobulin superfamily member 13) (IgSF13) (NK inhibitory receptor) (CD antigen CD300f) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000186074 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TDQ1 |
| Gene Card | CD300LF |
| Uniprot ID | Q8TDQ1 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.223742283) |
| Ortholog in Animals | Alpaca_ CD300LF ( ortholog_one2one ) GuineaPig_ CD300LF ( ortholog_one2one ) Macaque_ CD300LF ( ortholog_one2one ) Mouse_ Cd300ld4 ( ortholog_one2many ) Mouse_ Cd300ld ( ortholog_one2many ) Mouse_ Cd300ld5 ( ortholog_one2many ) Mouse_ Cd300ld3 ( ortholog_one2many ) Mouse_ Cd300ld2 ( ortholog_one2many ) Mouse_ Cd300lf ( ortholog_one2many ) Rat_ Cd300lf ( ortholog_one2many ) Rat_ AABR07030791.1 ( ortholog_one2many ) Rat_ Cd300le ( ortholog_one2many ) Rat_ AABR07030771.1 ( ortholog_one2many ) Rabbit_ CD300LF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TREML1, FCAMR, CD300LD, TMIGD3, CD300H, CD300C, CD300LG, CD300A, FCMR, PIGR, CD300E, TREM2, CD300LB |
| Tissue | lung, spleen, whole.blood |
| Tissue Specificity | Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells. {ECO:0000269|PubMed:15184070, ECO:0000269|PubMed:15549731}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2NMS (X-ray 2.60A ) |
| DBSNP | rs35489971 rs2034310 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |