| Gene Information | |
|---|---|
| Gene Name | SULT2A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 285 |
| Protein Names | Sulfotransferase 2A1 (ST2A1) (EC 2.8.2.2) (Bile salt sulfotransferase) (EC 2.8.2.14) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (DHEA-ST8) (Hydroxysteroid Sulfotransferase) (HST) (ST2) (SULT2A3) |
| Target Name | bile salt sulfotransferase |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000105398 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q06520 |
| Gene Card | SULT2A1 |
| Uniprot ID | Q06520 |
| Pfam | PF00685 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999646076) |
| Ortholog in Animals | Alpaca_ SULT2A1 ( ortholog_one2one ) Alpaca_ SULT2A1 ( ortholog_one2many ) GuineaPig_ Std2 ( ortholog_one2many ) GuineaPig_ Std1 ( ortholog_one2many ) Macaque_ SULT2A1 ( ortholog_one2one ) Mouse_ Sult2a1 ( ortholog_one2many ) Mouse_ Sult2a2 ( ortholog_one2many ) Mouse_ Sult2a6 ( ortholog_one2many ) Mouse_ Sult2a7 ( ortholog_one2many ) Mouse_ Sult2a8 ( ortholog_one2many ) Mouse_ Sult2a5 ( ortholog_one2many ) Mouse_ Sult2a3 ( ortholog_one2many ) Mouse_ Sult2a4 ( ortholog_one2many ) Pig_ SULT2A1 ( ortholog_one2one ) Rat_ Sult2a2 ( ortholog_one2many ) Rabbit_ SULT2A1 ( ortholog_one2one ) |
| Ohnologs | SULT4A1, SULT6B1, SULT1C3, SULT1C4, SULT1C2 |
| Paralogs | SULT1C2, SULT2B1, SULT1B1, SULT1C3, SULT6B1, SULT1C4, SULT1A2, SULT1A1, SULT1A4, SULT1A3, SULT1E1, SULT4A1 |
| Tissue | liver, adrenal.gland, small.intestine |
| Tissue Specificity | Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1EFH (X-ray 2.40A ) 1J99 (X-ray 1.99A ) 1OV4 (X-ray 2.70A ) 2QP3 (X-ray 2.60A ) 2QP4 (X-ray 3.00A ) 3F3Y (X-ray 2.20A ) 4IFB (X-ray 2.30A ) |
| DBSNP | rs772897551 rs11569681 rs775030275 rs751309613 rs368067020 rs757338859 rs779218418 rs11569679 rs753928755 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:2268288}. |
| Mouse PG classification | NA |
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