| Gene Information | |
|---|---|
| Gene Name | CCDC134 |
| Organism | Homo sapiens (Human) |
| Gene Length | 229 |
| Protein Names | Coiled-coil domain-containing protein 134 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100147 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H6E4 |
| Gene Card | CCDC134 |
| Uniprot ID | Q9H6E4 |
| Pfam | PF15002 |
| In ASD | no |
| Allosteric Prediction | no (-1.423827001) |
| Ortholog in Animals | Alpaca_ CCDC134 ( ortholog_one2one ) Dog_ CCDC134 ( ortholog_one2one ) GuineaPig_ CCDC134 ( ortholog_one2one ) Macaque_ CCDC134 ( ortholog_one2one ) Mouse_ Ccdc134 ( ortholog_one2one ) Pig_ CCDC134 ( ortholog_one2one ) Rat_ Ccdc134 ( ortholog_one2one ) Rabbit_ CCDC134 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | adrenal.gland, testis |
| Tissue Specificity | Expressed in cervical gland, cervical squamous epithelium, endometrium, stomach, kidney distal convoluted tubule, spermatogenic cells in testis, mammary gland, liver and striated muscle (at protein level) (PubMed:18087676, PubMed:23070808). Also detected in placenta (PubMed:18087676). Highest expression in testis relative to other tissues (PubMed:18087676). Detected in T cells and dendritic cells; highly expressed in activated CD8(+) T cells, and also expressed at lower levels in CD4(+) T cells (PubMed:25125657). {ECO:0000269|PubMed:18087676, ECO:0000269|PubMed:23070808, ECO:0000269|PubMed:25125657}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22644376}. Cytoplasm {ECO:0000269|PubMed:22644376}. Secreted {ECO:0000269|PubMed:18087676}. Endoplasmic reticulum {ECO:0000269|PubMed:18087676}. Note=Accumulates in the nucleus in response to UV irradiation (PubMed:22644376). {ECO:0000269|PubMed:22644376}. |
| Mouse PG classification | NA |
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