| Gene Information | |
|---|---|
| Gene Name | CASP10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 521 |
| Protein Names | Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000003400 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92851 |
| Gene Card | CASP10 |
| Uniprot ID | Q92851 |
| Pfam | PF01335 |
| In ASD | no |
| Allosteric Prediction | yes (0.199043673) |
| Ortholog in Animals | Alpaca_ CASP10 ( ortholog_one2one ) Dog_ CASP10 ( ortholog_one2one ) GuineaPig_ CASP10 ( ortholog_one2one ) Macaque_ CASP10 ( ortholog_one2one ) Pig_ CASP10 ( ortholog_one2one ) Rabbit_ CASP10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PYCARD, CASP14, CASP8, CASP2, CASP6, CFLAR, CARD18, CASP9, CASP1, CARD16, CASP5, CASP4, CASP3, CASP7, PYDC1, CASP12 |
| Tissue | NA |
| Tissue Specificity | Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.078382(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs559979934 rs121909776 rs41473647 rs17860403 rs80358239 rs13010627 rs28936699 rs41513147 rs17860405 rs13006529 rs13006529 rs13006529 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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