| Gene Information | |
|---|---|
| Gene Name | CARTPT |
| Organism | Homo sapiens (Human) |
| Gene Length | 116 |
| Protein Names | Cocaine- and amphetamine-regulated transcript protein [Cleaved into: CART(1-39); CART(42-89)] |
| Target Name | cocaine- and amphetamine-regulated transcript protein |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164326 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q16568 |
| Gene Card | CARTPT |
| Uniprot ID | Q16568 |
| Pfam | PF06373 |
| In ASD | no |
| Allosteric Prediction | no (-0.262729992) |
| Ortholog in Animals | Alpaca_ CARTPT ( ortholog_one2one ) Dog_ CARTPT ( ortholog_one2one ) GuineaPig_ CARTPT ( ortholog_one2one ) Macaque_ CARTPT ( ortholog_one2one ) Mouse_ Cartpt ( ortholog_one2one ) Pig_ CARTPT ( ortholog_one2one ) Rat_ Cartpt ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | adrenal.gland, hypothalamus |
| Tissue Specificity | Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1HY9 (NMR - ) |
| DBSNP | rs121909065 rs78242624 rs12517689 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | HPG |
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