Gene Information
Gene NameCAR
OrganismHomo sapiens (Human)
Gene Length352
Protein NamesNuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ14994
Gene CardNR1I3
Uniprot IDQ14994
PfamPF00104; PF00105
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityPredominantly expressed in liver.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001657(Rat);0.028571(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1XV9  (X-ray  2.70A  1XVP  (X-ray  2.60A 
DBSNP rs398122411 
Subcellular location [CC]Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7. {ECO:0000250}.
Mouse PG classificationNA
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