| Gene Information | |
|---|---|
| Gene Name | TMEM14A |
| Organism | Homo sapiens (Human) |
| Gene Length | 99 |
| Protein Names | Transmembrane protein 14A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000096092 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6G1 |
| Gene Card | TMEM14A |
| Uniprot ID | Q9Y6G1 |
| Pfam | PF03647 |
| In ASD | no |
| Allosteric Prediction | no (-1.238661579) |
| Ortholog in Animals | Alpaca_ TMEM14A ( ortholog_one2one ) GuineaPig_ TMEM14A ( ortholog_one2one ) Macaque_ TMEM14A ( ortholog_one2one ) Mouse_ Tmem14a ( ortholog_one2one ) Pig_ TMEM14A ( ortholog_one2one ) Rat_ Tmem14a ( ortholog_one2many ) |
| Ohnologs | TMEM14C, TMEM14B |
| Paralogs | TMEM14C, TMEM14B |
| Tissue | NA |
| Tissue Specificity | Expressed at significantly higher levels in ovarian cancer tissues than in normal tissues (at protein level). {ECO:0000269|PubMed:26896463}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LOO (NMR - ) 2LOP (NMR - ) |
| DBSNP | rs11543266 |
| Subcellular location [CC] | Mitochondrion membrane {ECO:0000269|PubMed:21723035}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21723035}. |
| Mouse PG classification | NA |
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