| Gene Information | |
|---|---|
| Gene Name | CAPN6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000077274 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6Q1 |
| Gene Card | CAPN6 |
| Uniprot ID | Q9Y6Q1 |
| Pfam | PF00168; PF01067; PF00648 |
| In ASD | no |
| Allosteric Prediction | no (-0.275198074) |
| Ortholog in Animals | Alpaca_ CAPN6 ( ortholog_one2one ) Dog_ CAPN6 ( ortholog_one2one ) GuineaPig_ CAPN6 ( ortholog_one2one ) Macaque_ CAPN6 ( ortholog_one2one ) Mouse_ Capn6 ( ortholog_one2one ) Pig_ CAPN6 ( ortholog_one2one ) Rat_ Capn6 ( ortholog_one2one ) Rabbit_ CAPN6 ( ortholog_one2one ) |
| Ohnologs | CAPN5 |
| Paralogs | CAPN1, PEF1, GCA, SRI, CAPN9, PDCD6, CAPN2, CAPN5, CAPN14, CAPN15, CAPN7, ADGB, CAPN8, CAPN3, CAPN12, CAPNS2, CAPN11, CAPN13, CAPNS1, CAPN10 |
| Tissue | placenta |
| Tissue Specificity | Expressed only in placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12013711 rs12851517 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:17210638}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17210638}. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle. |
| Mouse PG classification | NA |
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