| Gene Information | |
|---|---|
| Gene Name | WDR34 |
| Organism | Homo sapiens (Human) |
| Gene Length | 536 |
| Protein Names | Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96EX3 |
| Gene Card | DYNC2I2 |
| Uniprot ID | Q96EX3 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in several cell lines (at protein level). {ECO:0000269|PubMed:19521662}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.210714(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6RLB (EM 4.50A ) 6SC2 (EM 3.90A ) |
| DBSNP | rs201715229 rs148543026 rs587777091 rs587777092 rs587777096 rs587777098 rs587777094 rs587777093 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19521662, ECO:0000269|PubMed:25205765}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:19521662, ECO:0000269|PubMed:25205765}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:19521662}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:25205765}. Cell projection, cilium {ECO:0000269|PubMed:25205765}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q5U4F6}. Note=Concentrates around the centrioles and basal bodies also showing axonemal staining. {ECO:0000250|UniProtKB:Q5U4F6}. |
| Mouse PG classification | NA |
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