| Gene Information | |
|---|---|
| Gene Name | CAPG |
| Organism | Homo sapiens (Human) |
| Gene Length | 1015 |
| Protein Names | Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000042493 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BPX3 |
| Gene Card | NCAPG |
| Uniprot ID | Q9BPX3 |
| Pfam | PF12719 |
| In ASD | no |
| Allosteric Prediction | no (-0.220737441) |
| Ortholog in Animals | Alpaca_ CAPG ( ortholog_one2one ) Dog_ CAPG ( ortholog_one2one ) GuineaPig_ CAPG ( ortholog_one2one ) Macaque_ CAPG ( ortholog_one2one ) Mouse_ Capg ( ortholog_one2one ) Pig_ CAPG ( ortholog_one2one ) Rat_ Capg ( ortholog_one2one ) Rabbit_ CAPG ( ortholog_one2one ) |
| Ohnologs | SCIN, VILL |
| Paralogs | VIL1, VILL, SCIN, SVIL, AVIL, FLII, GSN |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis. {ECO:0000269|PubMed:10910072}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.025119(Rat);0.070145(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 6IGX (X-ray 3.00A ) |
| DBSNP | rs35722563 rs3795243 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase. |
| Mouse PG classification | NA |
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