| Gene Information | |
|---|---|
| Gene Name | CSNK1E |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1) |
| Target Name | casein kinase i epsilon |
| Target Type | Successful target |
| Gene Age | 987 ( ENSG00000213923 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49674 |
| Gene Card | CSNK1E |
| Uniprot ID | P49674 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.174156409) |
| Ortholog in Animals | Alpaca_ CSNK1E ( ortholog_one2one ) GuineaPig_ CSNK1E ( ortholog_one2one ) Macaque_ CSNK1E ( ortholog_one2one ) Mouse_ Csnk1e ( ortholog_one2one ) Pig_ CSNK1E ( ortholog_one2one ) Rat_ Csnk1e ( ortholog_one2one ) Rabbit_ CSNK1E ( ortholog_one2one ) |
| Ohnologs | CSNK1D |
| Paralogs | CSNK1D, CSNK1G3, TTBK2, VRK3, CSNK1A1L, VRK1, CSNK1G1, CSNK1A1, CDC7, CSNK1G2, VRK2, TTBK1 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.031095(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4HNI (X-ray 2.74A ) 4HOK (X-ray 2.77A ) |
| DBSNP | rs35665927 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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